Abstract: Performance prediction of shield driving plays an important role in evaluation of construction period and construction cost. Taking a construction lot of Guangzhou- Dongguan-Shenzhen intercity rail transit for example, a multivariate nonlinear regression analysis on advance rate of the EPB shield with diameter of 8.8 m in compound strata was conducted based on site data, a direct multivariate nonlinear prediction model, and a multivariate linear prediction model after linear treatment were established, the predicted and actual advance rates of the same section were compared. The results show that the error of advance rate measured by direct multivariate nonlinear prediction model is 9.035% compared with the actual advance rate, while the error of advance rate measured by multivariate linear prediction model after linear treatment is 5.987% compared with the actual advance.